pentobarbital will minimize the level or influence of armodafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.
pentobarbital increases toxicity of ifosfamide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. CYP3A4 inducers may boost the metabolism of ifosfamide to its Energetic alkylating metabolites.
Sodium valproate and valproic acid surface to minimize barbiturate metabolism; therefore, barbiturate blood stages needs to be monitored and acceptable dosage changes manufactured as indicated.
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pentobarbital will decrease the extent or influence of bedaquiline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Prevent coadministration of bedaquiline with powerful CYP3A4 inducers as a result of possible for diminished therapeutic impact
pentobarbital will minimize the level or effect of fentanyl transmucosal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead into a minimize in fentanyl plasma concentrations, insufficient efficacy or, possibly, improvement of the withdrawal syndrome in a patient who may have created Bodily dependence to fentanyl.
pentobarbital will lessen the extent or outcome of dasatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Though not advisable for a regimen method, hemodialysis can be Employed in critical barbiturate intoxications or In case the patient is anuric or in shock.
pentobarbital will lower the level or influence of solifenacin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
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pentobarbital will lessen the extent or impact of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Influence of coadministering a strong CYP3A4 inducer with fedratinib has not been studied.
pentobarbital will reduce the extent or result of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Coadministration of fentanyl with CYP3A4 inducers may lead to your lessen more info in fentanyl plasma concentrations, lack of efficacy or, probably, progress of a withdrawal syndrome in a very affected person that has designed physical dependence to fentanyl.
If you're thinking that there has been an overdose, simply call your poison Manage center or get healthcare treatment right away. Be all set to tell or show what was taken, exactly how much, and when it occurred.
pentobarbital will decrease the level or effect of triamcinolone acetonide injectable suspension by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.